Cancer patients’ own cells used to test treatments
The researchers used cells from a brain cancer patient to create a model of a tumor to test treatments before applying them to the body. The tumor model was created with 3d printing materials.
Scientists removed a piece of the tumor from a patient with glioblastoma and used it to print a model of the tumor. This explanation comes from Professor Ronit Satchi-Fainaro, who led the research at Tel Aviv University in Israel.
Glioblastoma is an aggressive form of brain cancer.
The patient’s blood is pumped through the imprinted tumor, then a drug or therapeutic the treatment is injected.
Previous studies have used similar methods of “bioprinting” to replicate cancerous environments. But Tel Aviv University researchers say they are the first to print a “viable“tumor.
Satchi-Fainaro said they have about two weeks to test different therapies on a tumor and find a treatment that’s right for the patient.
Treatment is considered promising if the imprinted tumor is shrinking or shrinking metabolic activity.
The research was published Wednesday in the publication Science Advances.
Glioblastoma is the most common form of brain cancer in adults. It quickly spreads to other parts of the brain, making it difficult to process. Survival is about 40 percent in the first year and 17 percent in the second. This information comes from the American Association of Neurological Surgeons.
Researchers often printed 3D tumor models to plan surgery. But more recent developments have used living cells as a kind of printing substance to build the parts of a tumor.
Ofra Benny is conducting similar research at the Hebrew University of Jerusalem. She said using a patient’s own cells to create 3D tumor models could “be a game-changer in personalized medicine.”
The more these 3D models are created, the better the prediction of how a treatment will work on the patient’s tumor, she said.
I am Alice Bryant.
Reuters News reported this story. Alice Bryant adapted it for Learn English. Susan Shand was the editor.
Words in this story
Tumor – nm a mass of tissue found in or on the body that is made up of abnormal cells
3d printing – nm the construction of a three-dimensional object from a computer model or a digital 3D model
Viable – adj. likely to be made or used
Metabolic – adj. from or related to metabolism
Surgery – n medical treatment in which a doctor cuts a person’s body in order to repair or remove damaged or diseased parts